منابع مشابه
SUMO wrestling with Ras
This review discusses our current understanding of the small ubiquitin-like modifier (SUMO) pathway and how it functionally intersects with Ras signaling in cancer. The Ras family of small GTPases are frequently mutated in cancer. The role of the SUMO pathway in cancer and in Ras signaling is currently not well understood. Recent studies have shown that the SUMO pathway can both regulate Ras/MA...
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In judo, making the opponent uncertain requires the mastery of several throws in 3 or 4 different directions and a firm grasp to secure the throw. The system of attacks for 28 judoka (18 men, 10 women) during their 185 respective matches over the competition season of 2001-2002 was analyzed. Practice was regional or interregional. The mean number of matches was 3.3+/-1.1. The mean number of suc...
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In the recent past, the clinical availability of genetic information has increased exponentially and with it the opportunity to use this information to aid in diagnosis and treatment of cardiovascular disease. One of the greatest challenges we face with this wealth of potentially useful diagnostic information is determining the pathogenicity of the myriad genetic variants identified. Dilated ca...
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A central methodological problem in programming with multiple levels of abstractions is the loosely defined problem of rep exposure. This paper traces the problem of rep exposure to the precisely defined notion of abstract aliasing. The paper also outlines a statically-enforceable discipline for avoiding abstract aliasing, but the outline is incomplete.
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Junior Chris Tripp brought his wrestling season to a brilliant close, crowned the Division II State Champion at 145 pounds in Columbus. Tripp finished the season with a 42-2 record, the school’s best ever. Senior co-captain Kevin Stone said, “Tripp had the work ethic and the will to be a state champion, and now he is. This is great for Chris and the wrestling program at US.” In the finals, Trip...
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ژورنال
عنوان ژورنال: British Journal of General Practice
سال: 2008
ISSN: 0960-1643,1478-5242
DOI: 10.3399/bjgp08x319864